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Role of phytoestrogens in the prevention and treatment of osteoporosis in ovarian hormone defficiency

Ovarian hormone defficiency is a major risk factor for osteophorosis in post minopausal women.
Hormone Replacement Therapy (HRT) is perhaps the most effective treatment, as it has been demonstrated to both reduce the rate of bone loss and risk of fracture, including hip fracture. Howevernot all women who may benefit from HRT are willing to initiate this treatment due to fear of cancer and contraindications. Other therapeutic agents currently available and also associated with certain adverse effects. As a result, postmenopausal women are more inclined to use natural remedies to alleviate postmenopausal symptoms and help reduce thier risk for chronic diseases such as Osteoporosis. Resent reports support the notion that certain bioactive constituents,e.g., phytoestrogens, in plants play a role in mentaining or improving skeletal healths. The main consumable plant sources of phytoestrogens include isoflavones and lignans found mainly is soy bean and flaxseed respectively. Although this paper primarily focuses on the effects of soy protien or its isoflavones on bone, additional statement regarding the role of flaxseed and dried plums, a rich source of polyphenols, with respect to bone will be made