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Role of
phytoestrogens in the prevention and treatment of osteoporosis in ovarian
hormone defficiency
Ovarian hormone defficiency is a major risk factor for
osteophorosis in post minopausal women.
Hormone Replacement Therapy (HRT) is
perhaps the most effective treatment, as it has been demonstrated to both reduce
the rate of bone loss and risk of fracture, including hip fracture. Howevernot
all women who may benefit from HRT are willing to initiate this treatment due to
fear of cancer and contraindications. Other therapeutic agents currently
available and also associated with certain adverse effects. As a result,
postmenopausal women are more inclined to use natural remedies to alleviate
postmenopausal symptoms and help reduce thier risk for chronic diseases such as
Osteoporosis. Resent reports support the notion that certain bioactive
constituents,e.g., phytoestrogens, in plants play a role in mentaining or
improving skeletal healths. The main consumable plant sources of phytoestrogens
include isoflavones and lignans found mainly is soy bean and flaxseed
respectively. Although this paper primarily focuses on the effects of soy
protien or its isoflavones on bone, additional statement regarding the role of
flaxseed and dried plums, a rich source of polyphenols, with respect to bone
will be made